Hyperalgesia and NMDA Receptor Antagonist

N/AUnknownNCT02087202

Seoul National University Bundang Hospital90 enrolled

Overview

NMDA receptor is administered and postoperative remote hyperalgesia is investigated.

NMDA receptor is adminstered and postoperative tertiary hyperalgesia is investigated. QST and pain measures for remote hyperalgesia are compared between control and magnesium or ketamine group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Pain

Interventions

Magnesium SulfateDRUG

magnesium sulfate is added to the patients

ketamineDRUG

ketamine is added to the patients.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA1-2 Exclusion Criteria: * contraindication to the study drugs

Outcomes

Primary Outcomes

pain

pain (QST and pain measures )until 1 month from the end of the operation

Time frame: until 1 month from the end of the operation

Data from ClinicalTrials.gov

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