Effect of Low-calorie Diet on Serum Lipids, Adipokines, Insulin Resistance and Also Body Composition in Women With Metabolic Syndrome

N/ACompletedNCT02087709

Universidade Federal do Rio de Janeiro30 enrolled

Overview

The purpose of this study is to evaluate the effect of a hypocaloric diet on biomarkers associated with insulin resistance, metabolic profile and body composition in women with Metabolic Syndrome.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Weight Loss Insulin Resistance Adipokines

Interventions

Low-calorie dietOTHER

Eligibility

Sex: FEMALEMin age: 30 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * BMI of 30-34.9 kg/m2, diagnostic of metabolic syndrome based on National Cholesterol Education Panel ATPIII (2002) Exclusion Criteria: * Diabetes mellitus, non-treated thyroid disease, treatment with lipid-lowering drugs and glucocorticoids or weight loss treatment within the previous 3 months.

Locations (1)

Federal University of Rio de Janeiro

Rio de Janeiro, Rio de Janeiro, Brazil

Outcomes

Primary Outcomes

Weight

Change from baseline weight (Kg) at 3rd month.

Time frame: Change from baseline at 3rd month

Secondary Outcomes

Insulin resistance markers

Change from baseline fasting glucose and insulin, homeostasis model assessment-insulin resistance and quantitative insulin sensitivity check index at 3rd month, samples were stored at -20 degrees.

Time frame: Change from baseline at 3rd month

Data from ClinicalTrials.gov

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