Alternative 10 mg/mL Liquid Formulation of ACY 1215 (Ricolinostat) in Healthy Subjects

Inclusion Criteria: * 18 to 65 years of age, inclusive * BMI range 18.5 to 32.0 kg/m2 * in good health, as determined by no clinically significant findings from medical history, 12-lead ECG, vital signs * clinical laboratory evaluations, CBC, coagulation, and UA * negative test for selected drugs of abuse * negative hepatitis panel and negative HIV antibody * females of non-childbearing potential as outlined in protocol * males either be sterile or agree to use contraception as outlined in protocol Exclusion Criteria: * significant history or clinical manifestation of any metabolic, allergic, dermatological, hepatic, renal, hematological, pulmonary, cardiovascular, gastrointestinal, neurological, or psychiatric disorder * history of significant hypersensitivity, intolerance, or allergy to any drug compound, food, or other substance * history of stomach or intestinal surgery or resection that would potentially alter absorption and/or excretion of orally administered drugs * history of Gilbert's Syndrome or suspicion of Gilbert's Syndrome * abnormality in the 12-lead ECG (e.g. QTcF of \>450 msec, a history of a prolonged QTc-interval or Brugada syndrome) * history of alcoholism or drug addiction within 1 year prior * participation in any other investigational study drug trial in which receipt of an investigational study drug as outlined in protocol * use of any prescription medications/products within 14 days (30 days for cytochrome P450 \[CYP\]-inducing or inhibiting products as outlined in protocol) * use of any over-the-counter, nonprescription preparations within 14 days * use of any tobacco or nicotine-containing products within 6 months and during study; * poor peripheral venous access * donation of blood from 30 days prior to Screening through the Follow-up visit * any acute or chronic condition that, in the opinion of the Investigator, would limit the subject's ability to complete and/or participate in this clinical study