Systematic Follow up of Drug Treatment by Pharmacists in Secondary Prevention After Transient Ischemic Attack

N/ACompletedNCT02089074

Norwegian University of Science and Technology265 enrolled

Overview

Use of drugs is an important factor in secondary prophylaxis after transient ischemic attack (TIA), but studies show that adherence to the prescribed drugs is often poor. This randomised controlled trial aims to investigate whether a systematic follow up of drug treatment using medication reconciliation, medication reviews and patient counselling by clinical pharmacists, improves adherence and/or decreases cardiovascular events the first three months and the first year after TIA. Patient satisfaction will also be compared between the two groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

265

Conditions

Ischemic Attack, Transient Stroke

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Probable or possible transient ischemic attack * Residing in Central Norway * Examined within 2 weeks after the onset of symptoms * Modified Rankin Scale 3 or less and living at home * enrolled in the MIDNOR-TIA study NCT02038725 * Informed consent

Locations (6)

Ålesund Sykehus

Ålesund, Norway

Kristiansund Sykehus

Kristiansund, Norway

Levanger Sykehus

Levanger, Norway

Molde Sykehus

Molde, Norway

Namsos Sykehus

Namsos, Norway

St Olavs Hospital

Trondheim, Norway

Outcomes

Primary Outcomes

adherence to drug treatment in secondary prevention after TIA

self reporting of adherence

Time frame: 3 months

Secondary Outcomes

adherence to drug treatment in secondary prevention after TIA

self reporting of adherence

Time frame: 1 year

Persistence

Persistence measured by control of filled prescriptions

Time frame: 3 months

Incidence of stroke and cardiovascular events and deaths

Measured by using data from national health registries

Time frame: 3 months

degree of disability or dependence in the daily activities

measured by modified Rankin Scale and indirectly by level of care

Time frame: 3 months

patient satisfaction

Measured by using data from the Norwegian Stroke Registry

Time frame: 3 months

Persistence

Persistence measured by control of filled prescriptions

Time frame: 1 year

Incidence of stroke and cardiovascular events and deaths

Measured by using data from national health registries

Time frame: 1 year

degree of disability or dependence in the daily activities

measured by modified Rankin Scale and indirectly by level of care

Time frame: 1 year

patient satisfaction

Measured by using data from the Norwegian Stroke Registry

Time frame: 1 year