Comparison of the Effect of Total Intravenous Anesthesia and Inhalation Anesthesia on Cancer Cell Cytotoxicity, Micrometastasis and Recurrence of Tumor in Patients Undergoing Breast Tumor Resection

Inclusion Criteria: * patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅲ * breast cancer patients with no sign of local invasion (adjacent organs) and distant metastasis revealed by imaging studies * surgery performed by the same surgical team Exclusion Criteria: * ASA physical status Ⅳ * hepatic and renal impairment * diabetes or other endocrine disorders * body mass index \> 35 kg/m2 * immune disorders or immunosuppressive therapy * steroid treatment in the last 6 months * inflammation