Laser Therapy Versus Electrosurgery For Nasal Telangiectasias

N/AWithdrawnNCT02090517

University of California, Davis

Overview

The aim of this study is to compare the efficacy of various treatment options for eliminating nasal telangiectasias. The study will compare the outcome of treating nasal telangiectasias with the following; no treatment (control site), alexandrite laser, pulsed dye laser, combination pulsed dye laser and Nd:YAG 1064nm multiplex laser system and electrosurgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Conditions

Telangiectasis

Interventions

Pulsed Dye LaserDEVICE

Pulsed dye laser treatments will be performed with a 595 nanometer wavelength, 20 millisecond pulse duration, at 10 Joules/cm2, with a 10 millimeter spot size.

Long Pulsed Alexandrite LaserDEVICE

Alexandrite laser will be used with a 755 nanometer wavelength, 40 millisecond pulse duration, at 88Joules/cm2, with a 6 millimeter spot size.

Pulsed Dye Laser Plus Nd:YAG LaserDEVICE

The Cynergy with MultiPlex will be used with a multiplex mode system with a pulse dye laser at 585 nanometer wavelength, 20 milliseconds pulse duration, at 7 Joules/cm2 with a 7 millimeter spot size, with a short delay, followed by a Nd:YAG 1064 nanometer wavelength, 20 millisecond pulse duration, at 50 Joules/cm2 with a 7 millimeter spot size.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Over 18 years of age * Able to give informed consent themselves * Willing to return for follow up visit * 0.5 - 3 millimeter Vessel size * 5 Non-contiguous nasal vascular lesions Exclusion Criteria: * Mentally handicapped * Unable to understand written and oral English * Incarceration * Under 18 years of age * Unwilling to return for follow up * Pregnant Women * Vessels less than 0.5 millimeter caliber * Less than 5 non-contiguous vessels

Locations (1)

University of California-Davis, Department of Dermatology

Sacramento, California, United States

Outcomes

Primary Outcomes

Reduction of Area of Nasal Telangiectasias by Laser Therapy Vs Electrosurgery

The study will measure the changes in length and width (area) of nasal telangiectasias before and after treatment with the following: no treatment (control site), alexandrite laser, pulsed dye laser, combination pulsed dye laser and Nd:YAG 1064nm multiplex laser system and electrosurgery.

Time frame: 3 months

Secondary Outcomes

Evaluation of Cosmetic Improvement

Percent perceived improvement for nasal vessels by the patient via questionnaire.

Time frame: 3 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.