Evaluation on Immunogenicity and Safety Profile of Trivalent OPV (tOPV Bio Farma)

Inclusion Criteria: * Healthy, full term, newborns infants * newborn residing within a relatively short and easily accessible distance A(\<30km) from the study clinic(s) and not planning to travel away during the entire study period * Infant born after 37 weeks of pregnancy * Infant weighing 2.5kg or more at birth (birth weight \>= 2.5kg) * Healthy newborns, with no history of asphyxia or meconium aspiration * Father, mother or legally acceptable representative properly informed about the study and having signed the informed consent form. * Parents will commit themselves to comply with the indications of the investigator and with the schedule of the trial * Mother at least elementary school graduate Exclusion Criteria: * Child concomitantly enrolled or scheduled to be enrolled in another trial * Known history of congenital or acquired immunodeficiency (including HIV infection) * Evolving moderate or severe illness, especially infectious diseases or fever (axillary temperature \>=37.5oC * Newborns requiring hospitalization at birth * Infant immunized with non-scheduled OPV or IPV during trial