FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma

N/AUnknownNCT02093715

Tel-Aviv Sourasky Medical Center400 enrolled

Overview

The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Acute Bronchiolitis

Eligibility

Sex: ALLMin age: 2 WeeksMax age: 2 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * First episode of shortness of breath * Children in ages 2 weeks to 2 years Exclusion Criteria: * Any chronic disease * Congenital anomalies

Locations (1)

Sourasky Medical Center

Tel Aviv, Israel

RECRUITING

Outcomes

Primary Outcomes

Physician diagnosed asthma

Modification of The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires

Time frame: At the age of 4 years

Secondary Outcomes

Fractional exhaled Nitric Oxide (FENO) level

FeNO level measured by a rapid-response chemiluminescence analyzer (Eco Physics CLD88 NO analyzer, EcoMedics AG,Switzerland).

Time frame: During acute bronchiolitis, after 2 and 6 months

Central Contacts

Yakov Sivan, Professor

CONTACT

sivan@tlvmc.gov.il

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.