To identify risk factors for aggressiveness in Squamous Cell Carcinoma of the skin in organ transplant recipients.
Squamous Cell Carcinomas (SCC) are one of the most common skin cancers. They belong to the epithelial neoplasm of the skin, which manifest a local aggressive growth and have potential for metastasis. Organ transplant recipients have a hundredfold higher incidence of SCC. Unfortunately the primary tumor, regional nodes, metastasis (TNM)-Classification for the prognosis of SCC in this group of patient has not yet been established. Therefore there are no standardised criteria for evaluation of local recurrence or prognosis. The aim of this study is to identify criteria, which permit a risk assessment relating to aggressiveness of SCC.
Study Type
OBSERVATIONAL
Enrollment
150
Universitätsspital Zürich
Zurich, Canton of Zurich, Switzerland
Diameter of Squamous Cell Carcinoma
* Location * exact size in mm * histological classification (well-differentiated, moderately-differentiated, poorly differentiated, spindle cell morphology, desmoplastic, basi-squamous, acantholytic) * Invasion * rapid growth * local recurrence * sentinel node sampling * Metastasis
Time frame: 1 year
Sun exposure history
* skin type * hair colour * eye colour * freckles * cumulative UV exposure Measurements will be assessed with questionnaire from about 150 participants.
Time frame: 1 year
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