Safety, Efficacy and PK/PD of POL7080 in Patients With Exacerbation of Non-cystic Fibrosis Bronchiectasis.

Inclusion Criteria: 1. Male and female aged ≥18 to \<80 years and suffering from exacerbation of non-cystic fibrosis bronchiectasis due to Pseudomonas aeruginosa infection 2. Sputum sample collected for culture before starting treatment Exclusion Criteria: 1. Female patients who are pregnant or breast feeding or unwilling to follow reliable method of contraception 2. Subjects suffering from cystic fibrosis, active pulmonary mycobacterial infection, end stage chronic obstructive pulmonary disease on long term oxygen therapy, severe uncontrolled asthma, active sarcoidosis and active allergic broncho-pulmonary aspergillosis 3. Current exacerbation of bronchiectasis is associated with lung abscess or empyema 4. Current exacerbation episode is suspected or documented to be due to pathogens other than Pseudomonas aeruginosa 5. Patients with known HIV infection with CD4+ (cluster of differentiation 4) cell count \< 200/mm3 6. Patients who are currently enrolled in, or have not yet completed at least 30 days since ending another investigational device or drug trial or are receiving other investigational agent