Preterm infants undergo very frequent painful procedures during neonatal care particularly during the first few days. The support for the pain of the preterm is a priority for nurses and neonatologists. Previous studies showed that non-nutritive sucking combined with sucrose ensures effective pain-relief for preterm (28-32 weeks GA). Unfortunately, the use of sucrose is limited to 4 administrations per day which is insufficient compared to the average of daily painful procedures. So, validation of an effective non-pharmacological intervention to relieve or avoid pain is essential. Facilitated tucking alone has been validated for preterm less than 37 GA during heel stick procedure with the PIPP score but no study looks for the benefit for pain relief of the association of non-nutritive sucking and facilitated tucking during heel stick procedure.
After randomization, baby will receive heel stick procedure with either non-nutritive sucking and sterile water or non-nutritive sucking and sterile water combined with facilited tucking. The sequence will be filmed. Evaluation of PIPP and DAN will be done after viewing by 3 independent experts. Each child will receive only one procedure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
60
Hôpital A.Trousseau La roche Guyon
Paris, France
PIPP (Premature Infant Pain Profile)
Behavioural measure of pain for premature infants. Indicators: * gestational age * behavioural state before painful stimulus * change in heart rate during painful stimulus * change in oxygen saturation during painful stimulus * brow bulge during painful stimulus * eye squeeze during painful stimulus * nasolabial furrow during painful stimulus
Time frame: 15 sec before to 30 sec after heel-lance procedure
DAN (Douleur Aigue Nouveau-né)
Behavioural measure of pain for premature infants Indicators: Facial movement Members movement Vocal expression
Time frame: 15 sec before to 3 min after heel-lance procedure
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