Associations of Exposure to Bisphenol A With Blood Pressure and Epigenetic Change

Overview

* Bisphenol A(BPA) is an endocrine disrupting chemical, which mimics the action of estrogen. * Previous studies reported that BPA exposure is associated with increased risk of cardiovascular diseases. * Exposure to BPA occur mainly through oral route, and epoxy coating of canned food is one of the well established source. * The investigators hypothesis is that increased BPA exposure from canned beverage would disrupt normal physiology in a short term. * In the present trial the investigators are to investigate whether increased BPA exposure by consuming canned beverage actually affect cardiovascular indices and epigenetic feature. * For this aim, the investigators will conduct a cross-over trial.

Conditions

Interventions