Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia

Key Inclusion Criteria: * Familial Chylomicronemia (Fasting triglycerides ≥ 880 mg/dL at Screening and documented history of plasma post-heparin LDL activity \< 20% of normal or genetic confirmation of homozygosity or compound heterozygosity for loss-of-function mutations in familial chylomicronemia-causing genes) OR * Non-familial Chylomicronemia (Fasting triglycerides ≥ 440 mg/dL at Screening and documented history of fasting triglycerides ≥ 880 mg/dL) Key Exclusion Criteria: * History of any major cardiovascular event within 6 months of Screening * Type I diabetes mellitus or use of insulin * History of pancreatitis within 3 month of Screening