Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON

N/ACompletedNCT02098668

University of Zurich123 enrolled

Overview

Development of a bio-mathematical model of the human female cycle

From hormonal measurements throughout 1-2 menstrual cycles in women with and without endocrinological pathology a mathematical model of the human menstrual cycle will be generated. The model will serve to predict development of the cycle including ovulation as well as to better understand the pathophysiology of endocrinological disorder. In a second step current treatment protocols for fertility treatment will be integrated into the model in order to optimize treatment outcome.

Study Type

OBSERVATIONAL

Enrollment

123

Conditions

Polycystic Ovary Syndrome Endometriosis Hyperprolactinemia

Interventions

Fertility treatmentOTHER

Fertility treatment

Eligibility

Sex: FEMALEMin age: 18 MonthsMax age: 43 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion criteria: \- Women during their reproductive phase, no hormonal therapy Exclusion criteria: \- Amenorrhoae

Locations (1)

University Hospital Zurich, Division of Reproductive Endocrinology

Zurich, Canton of Zurich, Switzerland

Outcomes

Primary Outcomes

Hormonal parameters

Development of a mathematical model of the menstrual cycle

Time frame: 3 years

Secondary Outcomes

Dynamics of fertility treatment

Mathematical model to improve fertility treatments

Time frame: 2 years

Data from ClinicalTrials.gov

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