This Phase 1 study aims to determine the oral bioavailability of a single dose of a new vapendavir tablet formulation and compare it to that of the previous vapendavir capsule formulation. The safety of both drug products will also be assessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
36
tablet - single dose
2 capsules - single dose
Investigative Site
Saint Paul, Minnesota, United States
Systemic exposure profile of a single dose of a vapendavir 300 mg tablet compared to the exposure profile following a single dose of two 132 mg vapendavir capsules
PK and statatistical analyses will be performed to determine the Primary Outcome Measure
Time frame: maximum up to 46 days
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