Effects of Antioxidant Dentifrice on Gingivitis

Inclusion Criteria: * Age between ≥ 20 and \< 65 y with at least 16 permanent teeth. * Gingival inflammation or mean baseline GI ≥ 0.5 without severe periodontal disease enough to require professional therapy. * Written informed consent to participate. Exclusion Criteria: * Taking medications that could influence periodontal tissue health, such as antimicrobials and antihypertensives within 1 month before starting the trial. * Use of orthodontic appliances. * Pregnancy or planning to become pregnant during the trial period. * Previous participation in any other clinical trial. * Inability of patient to understand the study purpose and/or study protocols. * Judged unsuitable by investigators for other reasons.