Treatment of Meibomian Gland Dysfunction and Dry Eye in Contact Lens Wearers

Inclusion Criteria: * Diagnosis of meibomian gland dysfunction and dry eye * At least 18 years of age * Willing to comply with randomization, attend all study visits and follow patient instructions * Habitual soft contact lens wearer 2 to 18 hours/day and 4 to 7 days/week * No change in contact lens type or dimensions for the past 3 months * Clinician assessment of acceptable contact lens fit and disinfecting solution * Tear film interferometry of 100 units or less Exclusion Criteria: * Systemic disease conditions that cause dry eye * Use of systemic medications known to cause dryness * History of any of the following ocular conditions in the past 3 months: surgery, trauma, Herpes infection, recurrent inflammation, punctal plug insertion or punctal occlusion * Presence of any of the following active conditions: ocular infection, ocular inflammation, moderate to severe allergic conjunctivitis, severe eyelid inflammation, eyelid abnormality that affects lid function, or ocular surface abnormality that compromises corneal integrity * Use of other treatments for meibomian gland dysfunction or dry eye except over the counter lubricants or dietary supplements * Participation in another ophthalmic drug or device trial in the past month * Employee, relative of employee or associate of the clinical site