The goal of this protocol is to establish a randomized clinical trial comparing the use of cord blood vs. infant blood with the primary outcome of comparing both the absolute hemoglobin concentration and the percent change in hemoglobin concentration from baseline around 24 hours of life.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
80
Tripler Army Medical Center
Honolulu, Hawaii, United States
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Carl R. Darnall Army medical Center
Fort Hood, Texas, United States
San Antonio Military Medical Center
Fort Sam Houston, Texas, United States
Absolute hemoglobin concentration
Time frame: 24 hours of life
Percent change in hemoglobin concentration from baseline
Time frame: 24 hours of life
Number/volume of packed red blood cell (pRBC) transfusions
Time frame: Participants will be followed from birth until time of hospital discharge, an expected average of 13 weeks
Number of blood donor exposures
Time frame: Participants will be followed from birth until time of hospital discharge, an expected average of 13 weeks.
Use of Vasopressors
Time frame: Participants will be followed from birth until time of hospital discharge, an expected average of 13 weeks.
Hemoglobin concentration at one week of life
Time frame: one week
Hemoglobin concentration at time of hospital discharge
Time frame: Approximately 10 - 16 weeks
Head Ultrasound
Time frame: Read at 7 Days of life and at hospital discharge which is approximately 13 weeks of age
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Portsmouth Naval Medical Center
Portsmouth, Virginia, United States
Madigan Army Medical Center
Tacoma, Washington, United States