Purpose of this study is to evaluate stem cell expression (SCE) in endometriotic (E) and non endometriotic ovarian and endometrial tissues.
This study was conducted on 40 women at Al-Azhar University Hospitals. They are divided into two equal groups, group 1 with ovarian endometrioma and group 2 with normal ovary. Ovarian and endometrial samples were evaluated by hematoxlin \& eosin for histopathology (HP) and of oct-4 for immunohistochemistry (IH) for SCE. Evaluation of IH parameters revealed that the most important factors for evaluating SC were arranged as score ( Edessy Stem Cell Score=ESS).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
80
Ovarian and endometrial samples were evaluated by hematoxlin \&eosin for histopathology (HP) and of oct-4 for immunohistochemistry (IH) for SCE
Al Azhar University
Cairo, Cairo Governorate, Egypt
Edessy Stem Cell Score (ESS)
ESS * Intensity of stem cell marker: Negative to mild =0, Moderate =1, Strong =2 * Percentage of stained cells: 0 =0, 0-50%= 1, \>50-100% =2. * Focality : None =0, Focal =1, Diffuse= 2 * Distribution: None= 0, Epithelial or mesenchymal= 1, Epithelial and mesenchymal= 2. * Localization of positive stained cell: None=0, Cytoplasmic or nuclear =1, Cytoplasmic and nuclear= 2
Time frame: 1 week
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