Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing

Inclusion Criteria: * prolonged neutropenia \> 10 d, patients * after allogeneic stem cell transplantation or solid organ transplantation, * Patients wth acute leukemia in induction treatment, * patients witrh graft-versus-host-disease, * patients under chronic immunusuppressive therapy such as ciclosporin, * patients with HIV, * patients with chronic steroid treatment Exclusion Criteria: * Age \< 18 years * missing informed consent * contraindication for pleural centesis