In this study the investigators propose to evaluate the performance of several G6PD testing platforms.
In this study we propose to evaluate the performance of several G6PD testing platforms. We will also determine the concordance between point-of-care G6PD tests and the spectrophotometric gold standard. This study will also access the sensitivity and specificity between the point-of-care G6PD tests. This study will take place in Indonesia, specifically in the SW Sumba region. We will enroll 700 volunteers.
Study Type
OBSERVATIONAL
Enrollment
700
Eijkman Institute for Molecular Biology
Jakarta, Indonesia
Determine concordance between point-of-care tests and spectrophotometric gold standard
Percent agreement between the quantitative results of the G6PD tests and the spectrophotometric test.
Time frame: Six months
Determine sensitivity and specificity of the point-of-care G6PD tests against the spectrophotometric gold standard
This is to determine the variance of the sensitivity and specificity of different G6PD point-of-care tests compared to the gold standard.
Time frame: Six months
Measure categorical accuracy of point-of-care G6PD test against by the spectrophotometric gold standard
Percent agreement between the qualitative G6PD test and the categorical results of the spectrophotometric gold standard
Time frame: Six months
Determine concordance between point-of-care G6PD tests and the florescent spot test
Compare sensitivity \& specificity of qualitative results of the G6PD test and the categorical results of the florescent spot test.
Time frame: Six months
Define the G6PD-normal and deficient profiles in the SW Sumba population.
Determine the profile of the SW Sumba area in regards to normal and deficient population spread.
Time frame: Six months
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