Intraarticular Xylitol Injections for Knee Osteoarthritis

Hadassah Medical Organization96 enrolled

Overview

Hypothesis: Intraarticular injections of isotonic Xylitol solution will improve pain in patients with knee osteoarthritis (OA).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Knee Osteoarthritis

Interventions

XylitolDEVICE

Eligibility

Sex: ALLMin age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age over 45 * Tibiofemoral osteoarthritis * OA stage 2-3 on xray * Pain VAS \> 40mm * No NSAIDs for 3 weeks * No analgetics for 38 hours Exclusion Criteria: * Pain VAS \> 80mm * Pain VAS in contralateral knee \> 40mm * Inflammatory arthritis * Severe effusion * Posttraumatic osteoarthritis * Unstable knee * Isolated patellofemoral disease * Paracetamol hypersensitivity

Locations (1)

Hadassah Medical Organization, Jerusalem, Israel

Jerusalem, Israel

Outcomes

Primary Outcomes

Pain - visual analogue scale

Time frame: 3 months

Central Contacts

Leonid Kandel, MD

CONTACT

+97225844500 kandel@hadassah.org.il

Data from ClinicalTrials.gov

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