First-in-Human Study of CLS003 ICVT in Subjects With Cutaneous Warts

Inclusion Criteria: * Healthy subjects (male, non-pregnant female), 18 to 65 years of age, inclusive. * Body mass index (BMI) between 18 and 30kg/m2, inclusive * Fitzpatrick skin type I-II-III-IV * At least 4 cutaneous warts on the hands, separated by at least 1cm of skin Exclusion Criteria: * For women, a positive pregnancy test and/or nursing at screening * A positive test for drugs of abuse at screening * History of alcohol or illicit drug abuse * Positive test results for Hepatitis B, Hepatitis C or HIV * Have used salicylic acid or any other over-the-counter- wart-removing product in the treatment area within 30 days prior to enrollment * Have received cryotherapy in the treatment area within 60 days prior to enrollment * Have required systemic intake of immunosuppressive or immunomodulatory medication (including oral or parenteral corticosteroids) with 30 days prior to enrollment or during the course of the study.