The purpose of this study is to determine whether DCVAC/OvCa added to chemotherapy may result in prolongation of Overall Survival (OS).
The purpose of this study is to determine whether DCVAC/OvCa added to Standard of Care chemotherapy may result in prolongation of Overall Survival (OS).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
22
DCVAC/OvCa is the experimental therapy added on to Paclitaxel or topotecan or doxorubicin
Paclitaxel or topotecan or doxorubicin is Standard of Care First Line Chemotherapy
Unnamed facility
Brno, Czechia
Unnamed facility
Nový Jičín, Czechia
Unnamed facility
Olomouc, Czechia
Unnamed facility
Ostrava, Czechia
Overall survival (all cause mortality)
Time frame: 72 weeks
Progression Free Survival
Per modified RECIST
Time frame: 72 weeks
Objective Response Rate
Per RECIST
Time frame: 0, 8, 16, ,24, 32, 40, 48, 56, 64, 72 weeks
Biological Progression Free Interval
Time frame: 0, 8, 16, 24, 32, 40, 48, 56, 64, 72 weeks
Immunological Response
Time frame: 0, 4, 8, 12, 16, 20, 24, 28, 32, 36, 40 weeks
Frequency of Adverse Events
Time frame: 0, 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 48, 56, 64, 72 weeks
Evaluation of Quality of Life via Functional Assessment of Cancer Therapy-Ovarian
Time frame: 0, 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 48, 56, 64, 72 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Unnamed facility
Prague, Czechia
Unnamed facility
Cologne, Germany
Unnamed facility
Dresden, Germany
Unnamed facility
Erlangen, Germany
Unnamed facility
Bialystok, Poland
Unnamed facility
Krakow, Poland
...and 2 more locations