The purpose of this study is to determine whether DCVAC/OvCa added to chemotherapy (carboplatin and gemcitabine as second line chemotherapy) may result in prolongation of progression free survival (PFS).
The purpose of this study is to determine whether DCVAC/OvCa added to Standard of Care chemotherapy (carboplatin and gemcitabine as second line chemotherapy) may result in prolongation of progression free survival (PFS).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
71
DCVAC/OvCa is the experimental therapy added on to Carboplatin and Gemcitabine
Carboplatin and Gemcitabine is Standard of Care First Line Chemotherapy
Unnamed facility
Brno, Czechia
Unnamed facility
Brno, Czechia
Unnamed facility
České Budějovice, Czechia
Unnamed facility
Determine median progression free survival
Time frame: 72 Week
Overall survival (all causes)
Time frame: 56, 64, 72 weeks
Objective Response Rate
Time frame: 8, 16, 24, 32, 40, 48, 56. 64. 72 weeks
Biological Progression Free Interval
Time frame: 6, 12, 18, 24, 36, 42, 48, 56, 64, 72 weeks
Immunological Response
Time frame: 24, 48, 72 weeks
Frequency of adverse events
Time frame: 8, 16, 24, 32, 40, 48, 56. 64. 72 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Hradec Králové, Czechia
Unnamed facility
Nový Jičín, Czechia
Unnamed facility
Olomouc, Czechia
Unnamed facility
Ostrava, Czechia
Unnamed facility
Prague, Czechia
Unnamed facility
Prague, Czechia
Unnamed facility
Cologne, Germany
...and 6 more locations