The aim of the present trial is to evaluate whether the conversion of immunosuppression from tacrolimus to cyclosporine A induces changes in (i) hepatitis C-virus load, (ii) parameters of hepatic function and (iii) parameters of glucose tolerance in hepatitis C-positive renal transplant recipients.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
conversion of immunosuppression from tacrolimus to cyclosporine A in hepatitis C-positive renal transplant recipients
Medical University of Vienna, Department of Internal Medicine III, Division of Nephrology and Dialysis
Vienna, State of Vienna, Austria
change in Hepatitis C-virus load at 12 weeks
Time frame: one day before and 4, 8 and 12 weeks after the conversion
change in oral glucose insulin sensitivity (OGIS) index at 12 weeks
Time frame: one day before and 12 weeks after the conversion
change in serum hepcidin levels at 12 weeks
Time frame: one day before and 12 weeks after the conversion
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