Prognostic Value of Progesterone on Oocyte Retrieval Day for In Vitro Fertilization Outcome

Acibadem University180 enrolled

Overview

This observational study aims the potential role of serum progesterone levels on the day of oocyte pick-up on the probability of pregnancy, in patients undergoing antagonist IVF cycles. There has been evidence, that increased serum levels of progesterone on triggering day are associated with a decreased probability of pregnancy after IVF. There is no study that investigate assocation between serum progesterone levels on the day of oocyte pick-up and IVF outcomes. This study will be the first in this case.

Study Type

OBSERVATIONAL

Enrollment

180

Conditions

Infertility Assisted Reproductive Technology

Interventions

Serum Progesterone LevelsOTHER

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 39 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age \< 40 years * Basal FSH \< 12 IU/L * Basal P \< 1.6 ng/mL Exclusion Criteria: * Women with polycystic ovaries syndrome (PCOS) * Women with Stage III-IV Endometriosis * Women with a pathological condition of the adrenal glands

Outcomes

Primary Outcomes

Clinical pregnancy

Clinical pregnancy, defined as ultrasound evidence of gestational sac at 6 weeks of gestation

Time frame: At 6-8 weeks of gestation

Data from ClinicalTrials.gov

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