The investigators assess in this study the sensitivity of Urea and Creatinine and that of Nitrazine test in vaginal wash after injecting saline in the vagina of patients with pre-labour rupture of membranes
The aim of this study is to compare the accuracy of measuring the urea and creatinine level versus that of nitrazine test in vaginal wash of pre-labour rupture of membranes patients.Each patient with rupture of membranes will be assessed clinically and then if not in labour , patients will be divided into 2 groups, 5ml saline will be injected in the vagina of each patient in every group then the vaginal wash will be collected in a test tube. Urea and creatinine group, biochemical tests for urea and creatinine in mIU/ml to detect their presence in the wash will be done. In Nitrazine group wash will be assessed by nitrazine paper showing bluish discoloration in rupture membranes. Sensitivity of each test in diagnosed rupture of membranes will be assessed.Which means how many patients in each test show positive results in case of diagnosed case.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
105
the vagina will be washed with 5ml saline, urea and creatinine will be detected biochemically in the vaginal wash.
Nitrazine detection in vaginal wash
the vagina will be washed with 5ml saline and vaginal wash will be collected.
Nesreen Abdel Fattah Abdullah Shehata
Cairo, Egypt
RECRUITINGUrea and creatinine in vaginal fluid
5ml saline will be injected vaginally then vaginal fluid will be collected.
Time frame: Within first 24 hours after rupture of membranes in third trimester
Nitrazine test
5ml saline is injected vaginally then vaginal fluid is collected
Time frame: Within first 24 hours after rupture of membranes in third trimester
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.