Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of

Tehran University of Medical Sciences99 enrolled

Overview

ABSTRACT: The aim of this study was to investigate the effect of betamethasone gel and lidocaine jelly (over tracheal tube cuff) compared with distilled water on the post intubation syndrome incidence. This study has not been carried out in Iran. 99 patients of either sex undergoing elective surgery were recruited in a single blind randomized study. The patients, using randomization table, were divided into three groups. Anesthetics and medications used during surgery were similar for all the patients. For the all patients, the incidence of postoperative sore throat, cough and hoarseness of the voice in the different follow-up periods (1, 6 and 24 hours) based on the different types of medications were obtained.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Sore Throat Cough

Interventions

Eligibility

Sex: ALLMin age: 15 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. 50 years\<age\>15 years 2. no acute upper respiratory infections and no sore throat 3. candidate for elective surgery unrelated to the throat 4. The lack of airways difficulties 5. candidate for general anesthesia with intubation 6. no contraindications for receiving steroid 7. surgery time \< 240 minutes 8. intubation up to 2 times 9. tracheal tube cuff pressure = 25-30 cm H2o 10. fasting for 8-6 hours prior to surgery 11. ASA I and ASAII and 12. Surgery under general anesthesia and endotracheal intubation Exclusion Criteria: 1. use of nasogastric tube or throat packs 2. patients with upper respiratory tract infection 3. patients on steroid therapy were excluded from the study

Outcomes

Primary Outcomes

sore throat

For the all the patients, the incidence of postoperative cough in 24 hours follow-up based on the different types of medications were obtained (using questionnaire).

Time frame: 24 hours after surgery

cough

For the all the patients, the incidence of postoperative cough in 1 hour follow-up periods based on the different types of medications were obtained (using questionnaire).

Time frame: 1 hour after surgery

hoarseness of voice

For the all patients, the incidence of postoperative hoarseness of the voice in 1 hour follow-up period based on the different types of medications were obtained (using questionnaire).

Time frame: 1 hour after surgery

sore throat

For the all the patients, the incidence of postoperative cough in 1 hour follow up based on the different types of medications were obtained (using questionnaire).

Time frame: 1 hour after surgery

sore throat

For the all the patients, the incidence of postoperative cough in 6 hours follow-up based on the different types of medications were obtained (using questionnaire).

Time frame: 6 hours after surgery

cough

For the all the patients, the incidence of postoperative cough in 6 hours follow-up periods based on the different types of medications were obtained (using questionnaire).

Time frame: 6 hours after surgery

cough

For the all the patients, the incidence of postoperative cough in 24 hours follow-up periods based on the different types of medications were obtained (using questionnaire).

Time frame: 24 hours after surgery

hoarseness of voice

For the all patients, the incidence of postoperative hoarseness of the voice in 6 hours follow-up period based on the different types of medications were obtained (using questionnaire).

Time frame: 6 hours after surgery

hoarseness of voice

For the all patients, the incidence of postoperative hoarseness of the voice in 24 hours follow-up period based on the different types of medications were obtained (using questionnaire).

Time frame: 24 hours after surgery

Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes