Investigators assume that there are some positive effects of cognitive training and physical activities on cognitive function, depression and quality of life in a sample of older residents in long-term care facilities. The purpose of this study is to explore the effects of various interventions (physical activity, cognitive training, integration of physical activity and cognitive training) on different outcome indictors in institutionalized older residents.
1. to develop an intervention protocol that achieves clinical development objectives in a scientifically rigorous and time efficient manner. 2. to further analyze the effects of the various interventions and make a comparison of dose-response relation and efficacy.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
270
group-based physical activity
individual-based, multi-domains cognitive training
National Taiwan Unversity Hospital
Taipei, Taiwan, Taiwan
RECRUITINGChange from Baseline Cognitive Function at 8 weeks and 16weeks
Cognitive Function: Cognitive Assessment Screening Instrument (CASI) 2.0 in Chinese version
Time frame: pre-treatment (0 week, T0), post-treatment (8 weeks, T1) and follow-up (16 weeks, T2 )
Change from Baseline Depression at 8 weeks and 16weeks
Depression: Geriatric depression scale (GDS)-15 in Chinese version.
Time frame: pre-treatment (0 week, T0), post-treatment (8 weeks, T1) and follow-up (16 weeks, T2 )
Change from Baseline Quality of Life at 8 weeks and 16weeksStatus:
Quality of Life: Short Form-12 (SF-12) in Chinese version.
Time frame: pre-treatment (0 week, T0), post-treatment (8 weeks, T1) and follow-up (16 weeks, T2 )
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