Effects of Green Tea Extract on Obese Women With High Level of LDL

National Yang Ming Chiao Tung University73 enrolled

Overview

Green tea is one of the most popular beverages in the world. It is believed to have beneficial effect in prevention and treatment of many diseases, one of which is reducing LDL-C. The aim of the study is to examine the effect of supplement containing GTE on obese with high LDL level.

Randomized, double-blind, crossover placebo-controlled clinical trial

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Obese Hyperlipidemia

Interventions

green tea extractDIETARY_SUPPLEMENT

500 mg three times per day

PlaceboDIETARY_SUPPLEMENT

cellulose 500mg three times a day for 6 weeks

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. age between 18 and 65 years 2. body mass index (BMI) \>= 27 kg/m2 3. fasting low-density-lipoprotein cholesterol (LDL) \>= 130mg/dl and (4) willing to participate in this trial. Exclusion Criteria: 1. serum alanine transaminase \> 80 U/L 2. serum creatinine \> 1.8 mg/dl 3. breast feeding or pregnancy 4. heart failure, acute myocardial infarction, stroke, heavy injury 5. any other conditions not suitable for trial as evaluated by the physician. -

Locations (1)

Taipei City Hospital

Taipei, Taipei, Taiwan

Outcomes

Primary Outcomes

percentage of reduction of LDL-C

level of LDL-C before intervention minus level of LDL-C after intervention equal to reduction of LDL-C, percentage of reduction of LDL-C equal to the level of reduction of LDL-C divided by level of LDL-C before intervention

Time frame: 6 weeks of treatment

Secondary Outcomes

HDL-C

serum level of high density lipoprotein cholesterol

Time frame: 6 weeks

Data from ClinicalTrials.gov

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