Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Assistance Publique Hopitaux De Marseille180 enrolled

Overview

This prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

180

Conditions

Acute Coronary Syndromes

Interventions

blood sampleOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * acute coronary syndrome (ST + \< 12 hours and ST- high risk or intermediate risk ),which there is an indication of percutaneous coronary intervention. Exclusion Criteria: * Cancer * Chronic inflammatory disease * Infectious disease * Erythrocyte \<4 G/l * Thrombopénia less than 100 000/mm3 ;

Locations (1)

assistance Publique Hopitaux de Marseille

Marseille, France

Outcomes

Primary Outcomes

evaluate the value of circulating endothelial progenitor cells quantification in the initial phase of ACS in predicting the occurrence of a major cardiovascular event (ECVM ) at 1 year.

Time frame: one year

Secondary Outcomes

determine the technical characteristics (sensitivity and specificity) and predictive value of the number of PEC

Time frame: one day , one month , one year

Data from ClinicalTrials.gov

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