* Compared with traditional open colectomy, laparoscopic surgery is associated with less pain, earlier recovery, and better cosmetic outcome, and its short- and long-term oncologic outcomes have been demonstrated. * In experienced surgeons' hands, single incision laparoscopic surgery is increasingly performed for colorectal disease, and even for malignant lesion because of its reduced incision-associated morbidity and scarring. * However, the safety and efficacy of single incision laparoscopic surgery for colorectal cancer has not yet been evaluated. Thus, the prospective randomized trial comparing single incision versus conventional laparoscopic surgery for colorectal cancer is needed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
198
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
RECRUITINGEarly morbidity rate
The early morbidity rate is defined as the event observed during operation and within 30 days after surgery,
Time frame: 30 days
Operative outcomes
Operative time, estimated blood loss and incision length are recorded.
Time frame: intraoperative
Pathological outecomes
Tumor size, length of proximal and distal margin and lymph nodes harvested are used to assess oncological resection.
Time frame: 5 days
Postoperative recovery course
Time to first ambulation, flatus, liquid diet, soft diet, and duration of hospital stay are used to assess the postoperative recoverty course.
Time frame: 14 days
Pain score
Postoperative pain is recorded using the visual analog scale (VAS) pain score tool on postoperative day 1, 2, 3 and the day of discharge.
Time frame: 14 days
Cosmetic assessment
Cosmetic assessment is perform using body image scale and cosmetic scale.
Time frame: 14 days
3-year disease free survival rate
Time frame: 36 months
5-year overall survival rate
Time frame: 60 months
Inflammatory and immune response
Time frame: 7 days
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