The main objective of the study is to show that the multidisciplinary review of drug prescriptions changes the adverse drug event (ADE) geriatric risk score (according to Trivalle and Ducimetière 2013) for patients living in the Nîmes University Hospital Residence for Dependent Elderly.
The secondary objectives of this study are to assess and compare the following criteria before and after multidisciplinary review of drug prescriptions for patients in the Nîmes University Hospital Residence for Dependent Elderly: A. the number of patients with at least one potentially inappropriate drug prescribed B. the number of hospitalizations C. death rate D. the number of falls per patient and the rate of fallers E. qualitative criteria describing the drug review F. associated care costs
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
49
The before-after study is composed of a first observational phase followed by a proactive phase, and then finally by a second observational phase. The first observational phase corresponds to retrospective data-collecting for the information necessary for calculating the baseline ADE geriatric risk score. The proactive phase corresponds to a multidisciplinary review of drug prescriptions (especially long-term drugs) for all included patients in the residence. During the second observational phase, the same data as in the first observational phase will be collected a second time.
CHRU de Nîmes - Centre de Gérontologie de Serre Cavalier
Nîmes, France
CHRU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, France
Adverse Drug Events Geriatric Risk Score
according to Trivalle and Ducimetière 2013
Time frame: change from Baseline to 6 months
The number of patients taking at least 1 potentially inappropriate drug according to Laroche criteria
Laroche et al 2007.
Time frame: During the proactive phase. Day 0.
Number of hospitalizations in the public sector (higher level care)
Time frame: first observational phase (month -6 to day 0)
Number of hospitalizations in the public sector (higher level care)
Time frame: second observational phase (day 0 to month 6)
Days of hospitalization in the public sector (higher level care)
Time frame: first observational phase (month -6 to day 0)
Days of hospitalization in the public sector (higher level care)
Time frame: second observational phase (day 0 to month 6)
Mortality
Time frame: first observational phase (month -6 to day 0)
Mortality
Time frame: second observational phase (day 0 to month 6)
The number of falls per patient
Time frame: first observational phase (month -6 to day 0)
The number of falls per patient
Time frame: second observational phase (day 0 to month 6)
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The percentage of patients who fell
Time frame: first observational phase (month -6 to day 0)
The percentage of patients who fell
Time frame: second observational phase (day 0 to month 6)
The Anatomical Therapeutic Chemical classification for each revised drug
Time frame: during the proactive phase (day 0)
The type of errors detected during drug review
Contra-indication, dosing, route, etc
Time frame: during the proactive phase (day 0)
The type of modification suggested during drug review
discontinuation, addition, substitution...
Time frame: during the proactive phase (day 0)
The acceptation rate for modifications suggested during drug review
Time frame: during the proactive phase (day 0)
Associated care costs (€)
Time frame: first observational phase (month -6 to day 0)
Associated care costs (€)
Time frame: second observational phase (day 0 to month 6)