Effect of Curodont Repair in Patients With Early Approximal Carious Lesions

Inclusion Criteria: * Two approximal carious lesions on different teeth with at least one tooth in between * Both study lesions must not require an invasive treatment * Size and form of the lesions: the lesions must be fully visible and assessable on radiographs * The two carious lesions must fall into classes: D1 (outer half of enamel) D2 (inner half of enamel) D3 (outer part of dentine) but only if very little dentine is involved (enamel-dentine junction) * Able and willing to observe good oral hygiene throughout the study * Age ≥ 18 years and ≤ 65 years * Willing and able to attend the on-study visits * Willing and able to understand all study-related procedures * Written informed consent before participation in the study Exclusion Criteria: * The two study test lesions are located on adjacent teeth * Fluoride varnish application \< 3 months prior to study treatment * Tooth with numerous carious lesions * Evidence of tooth erosion * History of head and neck illnesses (e.g. head/neck cancer) * Any pathology or concomitant medication affecting salivary flow or dry mouth * Any metabolic disorders affecting bone turnover * Patient suffers from diabetes * Concurrent participation in another clinical trial * Women who are breast-feeding, pregnant or who plan a pregnancy during the study * Women of childbearing potential who declare being unwilling or unable to practice contraception such as hormonal contraceptives, sexual abstinence or intercourse with a vasectomised partner