A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals

N/ACompletedNCT02119975

Erasmus Medical Center98 enrolled

Overview

Dysfunctioning executive functioning, including working memory (WM), is related to rumination. Findings show that working memory capacity (WMC) can be increased by training. The current study explored by means of a double-blind randomized controlled trial whether an adaptive WM training could reduce rumination, anxiety and depression in a sample of 98 depressed and anxious individuals.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Major Depression Anxiety Disorder

Interventions

Working memory trainingBEHAVIORAL

Placebo trainingBEHAVIORAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 67 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Major depression diagnosis * Anxiety diagnosis Exclusion Criteria: * Current psychosis * Substance abuse

Locations (1)

Erasmus University Rotterdam

Rotterdam, South Holland, Netherlands

Outcomes

Primary Outcomes

Change in Ruminative Response Scale (RRS) score from pre to post training and after two months (follow up 2)

Dutch version; Raes, Hermans, \& Eelen, 2003) measures the frequency of self-reported rumination behavior, with answer options ranging from 1 (never) to 4 (always). The total score of the 22 items was used in the analyses.

Time frame: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test)

Secondary Outcomes

Change in Beck Depression Inventory Second Edition (BDI-II) score from pre to post training and after two months (follow up 2)

The Beck Depression Inventory - II (BDI-II; Beck, Steer, \& Brown, 1996; Dutch version: Van der Does, 2002) measures the severity of depression symptoms of the last two weeks.

Time frame: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test)

Change in State-Trait Anxiety Inventory (STAI) score from pre to post training and after two months (follow up 2)

The State-Trait Anxiety Inventory (STAI; Spielberger, Gorsuch, Lushene, Vagg, \& Jacobs, 1983, Dutch version; Van der Ploeg, Defares, \& Spielberger, 1979) measures self-reported anxiety, divided in state anxiety and trait anxiety.

Time frame: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test)

Data from ClinicalTrials.gov

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