POST-dilatation to Improve Outcomes in Acute STEMI Patients Undergoing Primary With OCT Assessment

Clinical Inclusion Criteria: * Age ≥18 years * STEMI \>20 mins and \<12 hours in duration * ST-segment elevation of ≥1 mm in ≥2 contiguous leads; or Presumably new left bundle branch block; or True posterior MI with ST depression of ≥1 mm in ≥2 contiguous anterior leads * Written, informed consent Angiographic Inclusion Criteria * The presence of least 1 acute infarct artery target vessel\* in which: 1. ALL significant lesions are eligible for stenting with study stents, and 2. ALL such lesions have a visually estimated reference diameter ≥2.5 mm and ≤4.0 mm 3. All culprit lesion TIMI Flow ≤ 0 or 1 Grade prior to guide wire crossing * Expected ability to deliver the stent(s) to all culprit lesions (absence of excessive proximal tortuosity or severe calcification) * Expected ability to fully expand the stent(s) at all culprit lesions (absence of marked calcification) Clinical Exclusion Criteria: * Contraindication to any of the study medications * Patients with cardiogenic shock * History of bleeding diathesis or known coagulopathy , or will refuse blood transfusions * History of intracerebral mass, aneurysm, AVM, or hemorrhagic stroke; stroke or TIA within 6 months or any permanent neurologic deficit; GI or GU bleed within 2 months, or major surgery within 6 weeks; recent or known platelet count \<100,000 cells/mm3 or hgb \<10 g/dL * Planned elective surgical procedure that would necessitate interruption of thienopyridines during the first 6 months post enrollment Angiographic Exclusion Criteria * Bifurcation lesion definitely requiring implantation of stents in both the main vessel + side branch * Infarct related artery is an unprotected left main * \>38 mm of study stent length anticipated * Infarction due to stent thrombosis, or infarct lesion at the site of a previously implanted stent * High likelihood of CABG within 30 days anticipated * The culprit lesion will be judged unsuitable for OCT procedure, because of conditions such as left main trunk disease or shock vital