Colchicine in Coronary Artery Bypass Graft (CABG)

Inclusion Criteria: * The study will enroll patients 18 years old or older who are eligible to undergo CABG surgery. Exclusion Criteria: Excluded are patients: * with age \> 80 years old * scheduled for concomitant valve surgery * scheduled for coronary surgery without cardiopulmonary bypass * with peripheral vascular disease affecting the upper limbs * with acute coronary syndrome within the previous 4 weeks * on inotropic or mechanical circulatory support before induction of anaesthesia * with any disorder that could potentially increase preoperative cTnI concentrations (eg, percutaneous coronary intervention within the previous 6 weeks) * with active inflammatory diseases, infectious diseases or known malignancy * under treatment with corticosteroids, anti-inflammatory agents or disease modifying agents * with known hypersensitivity-allergy to colchicine * under chronic treatment with colchicine * with severe renal failure (eGFR \< 35 ml/min/1.73 m2) * with hepatic failure (Child - Pugh class B or C)