Prospective, randomized clinical multicentric study in ICU during weaning from mechanical ventilation.
Prospective randomized clinical multicentric study on ICU comparing a treatment strategy (nasal humidified high flow therapy and Noninvasive Ventilation) in patients with high-risk of postextubation distress in ICU based on a Lung Ultrasound Score VERSUS standard strategy
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
483
Prospective randomized clinical multicentric study on ICU comparing a treatment strategy (nasal humidified high flow therapy and Noninvasive Ventilation) in patients with high-risk of postextubation distress in ICU based on a Lung Ultrasound Score VERSUS standard strategy
CHU de Clermont-Ferrand
Clermont-Ferrand, France
Incidence of postextubation distress
postextubation period requiring a ventilatory support (reintubation or curative Noninvasive ventilation).
Time frame: during 48 hour (at day 1)
Number of ventilator-free-days
Time frame: at day 1 (after extubation)
Length of stay in ICU
Time frame: at day 1
Mortality in ICU
Time frame: at day 1
Extubation failure
Extubation failure within the 7 days following planned extubation
Time frame: at day 7
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