Living Donor Liver Transplantation in Children

Cliniques universitaires Saint-Luc- Université Catholique de Louvain500 enrolled

Overview

Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.

Data from 250 pediatric LDLT recipients (and their donors), transplanted at Cliniques universitaires Saint-Luc between July 1993 and June 2012, were collected retrospectively using electronic data files. Results were analysed according to ABO matching and portal vein complications. Uni- and multi-variate analysis was used to study the impact of immunosuppression, gender match and maternal donation on acute rejection rate.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Pediatric Liver Transplanted Recipients Healthy Donors

Eligibility

Sex: ALLMax age: 57 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Children receiving a living donor liver transplant * Adult living donors Exclusion Criteria: * No one

Outcomes

Primary Outcomes

Patient and graft survival

Kaplan-Meier

Time frame: 10 years

Secondary Outcomes

Portal vein complications

Time frame: 10 years

Data from ClinicalTrials.gov

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