Single Center Comparison of 4 FDA Approved, Commercially Available Bowel Purgatives for Colonoscopy

Inclusion Criteria: 1. Age 18 years or greater 2. Ability to understand and complete questionnaires 3. Ability to speak and read English 4. Willingness to participate in study 5. Colonoscopy is being performed for routine screening (i.e. no prior personal history of polyps or cancer) or surveillance (i.e. follow up for a personal history of polyps) purposes Exclusion Criteria: 1. Previous bowel resection of any kind (small or large bowel) 2. End stage renal disease (ESRD) 3. Contraindication to bowel purgative 4. Necessity for inpatient admission to receive bowel preparation for any reason 5. Currently taking any narcotic/opiate pain or anticholinergic medication (since these may predispose to higher colon stool burden at baseline) 6. Currently taking stool softeners (e.g. Miralax, Amitiza, Linzess, lactulose) or stimulant laxatives (e.g. Dulcolax) 7. Subject did not follow appropriate dosing instructions for bowel purgative 8. Colonoscopy is being performed to evaluate a clinical symptom such as rectal bleeding, constipation, abdominal pain, or diarrhea 9. History of colon polyposis syndrome 10. Personal history of inflammatory bowel disease 11. History of inadequate colon preparation on any prior colonoscopies 12. Patient is pregnant