The purpose of this study is to assess the long-term persistence of immunity to hepatitis A in adults who were vaccinated 21-25 years earlier with hepatitis A vaccine, Havrix®.
This is a long-term persistence study in which subjects who participated in the primary studies HAV-112 (208109/108) or HAV-123 (208109/114) and did not receive an additional dose of hepatitis A vaccine since then, will be invited to provide a blood sample at Years 21 to 25 after their second vaccine dose. No vaccine will be administered during the study period.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
At Years 21 to 25 after their second vaccine dose.
GSK Investigational Site
Wilrijk, Belgium
Immunogenicity with respect to components of the study vaccine in terms of anti-HAV seropositivity status and GMCs.
Time frame: 21 to 25 years after the second vaccine dose.
Occurrence of serious adverse events (SAEs).
Time frame: During the entire study period (Year 21 to Year 25).
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