Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection

Centro Universitario de Lavras77 enrolled

Overview

Evaluate and compare the effectiveness in a clinical and microbial perspective one stage full-mouth disinfection technique in relation to scaling and root planing per quadrant associated with chlorhexidine or azithromycin.

Seventy -seven systemically healthy subjects with chronic periodontitis were randomly included in 6 different predefined groups. The following periodontal parameters were evaluated: probing depth , clinical attachment level , plaque index, gingival index and percentage of areas affected by periodontal disease. Microbiologically were evaluated the bacterial load and specific load of five bacterias: The quantification of the bacteria was performed by real-time Polymerase Chain Reaction . The clinical and microbial baseline evaluations were performed ( periodontal pre- therapy) , 90 and 180 days after treatment.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Periodontal Disease Chronic Periodontitis

Interventions

Scaling and root planingPROCEDURE

Scaling procedures were performed per quadrant (30 min. per quadrant) at weekly intervals between sessions;

Full mouth disinfectionPROCEDURE

Procedures for scaling and root planing were performed in a single stage (24 hours) divided into two sessions (60 min per session) on two consecutive days

Chlorhexidine gel and gluconateDRUG

application of chlorhexidine (CX) (1%) gel in pockets after scaling, brushing tongue for 1 min. with CX (1%) gel and mouthwash at the beginning and end of each session with CX 0.2% for 30 seconds (with the form of a gargle in the last 10 seconds)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of slight-moderate chronic periodontitis Exclusion Criteria: * Those who were making regular use of antibiotics or anti-inflammatory drugs or had done up to three months before the beginning of the study; * those who were making regular use (twice a day) of oral rinses with chlorhexidine or essential oils or have made regular use within three months prior to study entry; * individuals with a history of sensitivity to chlorhexidine or azithromycin; * subjects undergoing periodontal therapy include dental scaling procedures in the 12 months preceding the start of the study; * subjects with impaired bifurcation or trifurcation class III; * who required antibiotic prophylaxis for conducting clinical periodontal examination * subjects with removable partial dentures and removable or fixed orthodontic appliance.

Locations (1)

Douglas Campideli Fonseca

Lavras, Minas Gerais, Brazil

Outcomes

Primary Outcomes

Change in clinical attachment

In this parameter we will evaluate the distance from the cement-enamel junction to the bottom of the periodontal pocket or gingival sulcus. This measurement is made with a periodontal probe graduated in millimeters

Time frame: Baseline and 180 days after treatment

Secondary Outcomes

Change in probing depth

In this parameter we will evaluate the distance between the gingival margin and the bottom of the periodontal pocket or gingival sulcus. This measurement is made with a periodontal probe graduated in millimeters

Time frame: Baseline and 180 days after treatment

Data from ClinicalTrials.gov

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