Pharmaceutical Consultation at Hospital Discharge and Adherence to Anti-infective Treatment

Centre Hospitalier Universitaire de Nīmes174 enrolled

Overview

The main objective of this study is to evaluate the impact of a pharmaceutical consultation at the time of hospital discharge on the adherence of patients ; non-adherence is determined by the following criteria: As concerns prescribed anti-infectious treatments, at least one of the following 4 criteria is true: 1. . the patient did not go and get his/her treatment at the pharmacy; 2. . the number of treatment units dispensed by the pharmacy is \< the number of treatment units prescribed; 3. . the patient stopped taking a treatment before the recommended time, or continued taking a treatment after the recommended time; 4. . the number of treatment units taken by the patient (self-declaration) is \< or \> to the number of units prescribed.

The secondary objectives of this study are : A- To assess the percentage of patients who obtained their anti- infective pharmaceuticals B- To evaluate the ratio of the number of units of anti- infective drugs dispensed by the pharmacy over the number of units of anti- infective drugs prescribed C- To determine the ratio of the number of premature discontinuations of anti -infective treatments over the number of lines of anti -infective treatments prescribed D- Evaluate the ratio of the number of units actually taken by the patient (based on a self-declaration) over the number of units of anti- infective drugs prescribed E- To measure the comprehension concerning anti- infective treatments after returning home (based on a quiz) F- To determine the risk factors for non- adherence to anti- infective therapy based on the characteristics of the study population G- Assess patient satisfaction concerning a pharmaceutical consultation at hospital discharge (questionnaire) H- Assess the impact of a pharmaceutical consultation on primary non-adherence (criteria 1 and 2) and secondary non- adherence (criteria 3 and 4)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The patient is hospitalized in the Infectious and Tropical Diseases department of the Nîmes University Hospital, and is scheduled for hospital discharge with one or more pharmaceutical prescriptions for anti-infectious treatments Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient resides in a care establishment, or has home medical/nursing service * The patient is suffering from chronic infection (\>4 weeks of treatment required) * The patient is suffering from handicapping deafness, dementia, or does not have a telephone * Intravenous, intramuscular or subcutaneous anti-infectious treatments are prescribed * Prescription of antiretroviral treatments

Outcomes

Primary Outcomes

The presence/absence of treatment non-adherence

As concerns prescribed anti-infectious treatments, at least one of the following 4 criteria is true: 1. . the patient did not go and get his/her treatment at the pharmacy; 2. . the number of treatment units dispensed by the pharmacy is \< the number of treatment units prescribed; 3. . the patient stopped taking a treatment before the recommended time, or continued taking a treatment after the recommended time; 4. . the number of treatment units taken by the patient (self-declaration) is \< or \> to the number of units prescribed.