Pharmacological Conditioning of Sleep Patterns in Healthy Participants Using Amitriptylin

Inclusion Criteria: * age between 18 years to 69 years * willingness to refrain from alcohol consumption throughout the study * regular sleeping habits * fluent in German language * is not dependent on driving to get to the study center * provide written informed consent * ability to understand the explanations and instructions given by the study physician and the investigator Exclusion Criteria: * Contraindications to study medication intake according to the information sheet for health professionals (Summary of medicinal Product Characteristics, SmPC) assessed by physical examination (including ECG) and medical history * allergies to amitriptyline hydrochloride or any of its ingredients * acute intoxication with alcohol, analgetics, hypnotics or any other psychotropic drug * urinary retention * delirium * untreated closed-angle glaucoma * prostatic hyperplasia * pyloric stenosis * paralytic ileus * suicidal thoughts * liver/ kidney/ pulmonary insufficiency * myasthenia gravis * hypokalemia * bradycardia * coronary heart disease, cardiac arrhythmias, long QT syndrome or other clinically relevant cardiac disorders * increased risk of seizures/ history of seizures * substance dependence syndrome/ history of substance dependence syndrome * Allergies to ingredients of placebo or novel-tasting drink (CS) * currently pregnant (verified by urine pregnancy test) or lactating * patients suffering from a mental disorder as verified by the International Diagnosis Checklists (IDCL) * patients suffering from a medical condition (assessed by the study physician) * Concomitant medication interfering with study medication intake due to potential interactions * participation in any other clinical trial 3 months prior to visit 1 * employee of the Sponsor or the principal investigator