The purposes of this study are to assess the efficacy, safety and tolerability of a single dose of REGN1908-1909 in allergic adult participants, to collect information about how much REGN1908-1909 is in blood over time and to collect information about how the body reacts to REGN1908-1909.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
74
Unnamed facility
Groningen, Netherlands
Unnamed facility
Auckland, New Zealand
Unnamed facility
Christchurch, New Zealand
Unnamed facility
Lund, Sweden
Unnamed facility
London, United Kingdom
Change in allergic symptom scale score
The primary endpoint is the change in allergic symptom scale score at day 8
Time frame: At day 8
Incidence rate of treatment-emergent adverse events (TEAEs) through day 85 in participants treated with REGN1908-1909 or placebo
Time frame: day 1 to day 85
Pharmacokinetic (PK) parameters of REGN1908- REGN1909 administration (i.e. how much REGN1908-1909 is in blood over time and how the body reacts to REGN1908-1909)
Time frame: day 1 to day 85
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