Obese patients undergoing bariatric surgery warrant VTE prophylaxis because they are at high risk for developing a fatal pulmonary embolism or postthrombotic syndrome. However, a consensus does not exist on the most effective prophylactic approach.
Two regimens of prophylaxis are supposed , the 1st one is to give enoxaparin 40mg 2 hours before surgery and continued daily for 10 days after, and the 2nd one is to start 12 hours before surgery and continued in the same way like the 1st one.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
700
Enoxaparin 40 mg 2 hours before surgery
Enoxaparin 40 mg 12 hours before surgery
Manoura University
Al Mansurah, Egypt
RECRUITINGVenous thrombosis and/or pulmonary embolism (PE)
To assess the venous thrombosis by compression ultrasonography and PE in suspected patients
Time frame: Postoperative 4 weeks
Bleeding from the surgery site , drain if any, GIT bleeding,
Bleeding from drain, GIT, or wounds are assessed clinically
Time frame: postoperative 4 weeks
hospital stay
hospital stay in days
Time frame: 4 WEEKS
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