Predictive Value of Periodic Repolarization Dynamics in Post-Infarction Patients

Thebiosignals.com754 enrolled

Overview

Increased periodic repolarization dynamics (PRD) indicate increased risk of death in cardiac patients. This study thoughts to prospectively validate the prognostic value of PRD in post-infarction patients.

Periodic repolarization dynamics (PRD) reflect periodic changes of repolarization instability located in the low-frequency spectral range. Level of PRD can be assessed using a high resolution surface ECG recorded in the 12-leads of Frank leads configuration during resting conditions. Increased levels of PRD have been associated with sympathetic overactivity and increased risk of mortality in survivors of acute myocardial infarction and patients undergoing a clinically indicated exercise test.

Study Type

OBSERVATIONAL

Enrollment

754

Conditions

Myocardial Infarction

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * previous myocardial infarction \>4 weeks * age \>18 years Exclusion Criteria: * life expectancy \< 1 year due to non-cardiac causes * unable to give informed consent

Locations (1)

Eberhard-Karls-University Tuebingen

Tübingen, Baden-Wurttemberg, Germany

Outcomes

Primary Outcomes

Number of total deaths

Time frame: 24 months

Secondary Outcomes

Number of cardiovascular deaths

Time frame: 24 months

Data from ClinicalTrials.gov

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