The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.

HaEmek Medical Center, Israel82 enrolled

Overview

In total 50 subjects with iron deficiency anemia treated with intravenous iron are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant before iron treatment. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). patient will go face to face interview and will be asked to answer structured questionnaire which will include information on demographics, clinical data ( fever, allergies , etc.) and comorbidities Two weeks after completing intravenous iron administration additional blood samples will be taken: thrombin generation will be measured

Study Type

OBSERVATIONAL

Enrollment

Conditions

Iron Deficiency Anemias

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 years * Iron deficiency anemia that did not response to oral iron treatment and is planned to receive iron supplement intravenously. * Signing the informed consent exclusion criteria: * chronic inflammatory disease * renal failure * Malignancy * Infectious disease * Other reason for anemia except iron deficiency anemia. * Pregnant women * Use of anti aggregating agents or anticoagulants

Locations (1)

Haemek medical center

Afula, Israel

The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes