Spectrophotometric Evaluation of Chlorhexidine Pigmentations After Oral Surgery: a Prospective Randomized Clinical Trial

dott. Lorenzo Bevilacqua60 enrolled

Overview

The aim of this clinical trial was to evaluate through a clinical spectrophotometric analysis the staining side effect of a 0.2% CHX mouthwash containing an anti discoloration system (ADS) compared with a 0.12% and a 0.2% CHX alone mouthwash after periodontal surgery. The efficacy of the products and the patient's opinion and acceptance were also assessed.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Staining Effect of Chlorhexidine

Interventions

ChlorhexidineDRUG

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Good general health conditions without a medical history of medication that might interfere with periodontal tissues * Good plaque control (FMPS ≤ 25%) and low levels of infection (FMBS ≤ 25%) * Need for periodontal surgery Exclusion Criteria: * Smokers * Allergy to CHX * Lack of written informed consent

Locations (1)

Ospedale Maggiore

Trieste, Italy, Italy

Outcomes

Primary Outcomes

Change in ΔE before and after the use of chlorhexidine

Change in ΔE before and after the use of chlorhexidine (ΔE is a measurement used to indicate how much a color deviates from an accepted standard. Perfect color has a ΔE of zero.)

Time frame: Change from Baseline of ΔE after the use of chlorhexidine mouthrinses; change from Baseline of ΔE after the use of chlorhexidine mouthrinses at 1 week; change from Baseline of ΔE after the use of chlorhexidine mouthrinses at 2 weeks

Data from ClinicalTrials.gov

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